Generic name: glycopyrrolate (oral) [ GLY-koe-PIE-roe-late ]
Brand names: Cuvposa, Robinul, Robinul Forte
Drug class: Anticholinergics / antispasmodics

What is Robinul?

Robinul helps to control conditions such as peptic ulcers that involve excessive stomach acid production.

Robinul is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy.

Robinul may also be used for purposes not listed in this medication guide.

Important Information

You should not use Robinul if you have urination problems, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, myasthenia gravis, or active bleeding with heart and blood circulation problems.

Before taking this medicine

You should not use Robinul if you are allergic to it, or if you have:

• a bladder obstruction or other urination problems;

• a stomach or bowel obstruction (including paralytic ileus);

• severe constipation;

• severe ulcerative colitis or toxic megacolon;

• glaucoma;

• myasthenia gravis; or

• active bleeding with fast heartbeats, low blood pressure, shortness of breath, and cold hands or feet.

Tell your doctor if you have ever had:

• liver or kidney disease;

• heart problems or a heart rhythm disorder;

• high blood pressure;

• a stomach disorder such as ulcerative colitis, hiatal hernia, reflux disease, or slow digestion;

• a colostomy or ileostomy;

• a thyroid disorder; or

• a nerve disorder.

It is not known whether Robinul will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using Robinul. This medicine may slow breast milk production.

Do not give this medicine to a child without medical advice.

How should I take Robinul?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may need to take Robinul on an empty stomach, at least 1 hour before or 2 hours after a meal. Follow the instructions provided with your medicine.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Robinul doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe muscle weakness, loss of movement, dilated pupils, jerky muscle movements, or seizure (convulsions).

What should I avoid while taking Robinul?

Avoid driving or hazardous activity until you know how Robinul will affect you. Your reactions could be impaired.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Robinul can decrease sweating and you may be more prone to heat stroke.

Drinking alcohol with this medicine can cause side effects.

Robinul side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Robinul and call your doctor at once if you have:

• severe constipation, severe stomach pain and bloating;

• diarrhea (especially if you have a colostomy or ileostomy);

• painful or difficult urination;

• fast or pounding heartbeats, fluttering in your chest;

• confusion, severe drowsiness;

• fever, shallow breathing, weak pulse, hot and red skin; or

• (in a child taking Robinul) dry diapers, fussiness, or excessive crying.

Common side effects may include:

• constipation, nausea, vomiting, bloating;

• drowsiness, dizziness, weakness, feeling nervous;

• sleep problems (insomnia);

• blurred vision;

• dry mouth, decreased sense of taste;

• decreased sweating, decreased urination;

• impotence, sexual problems;

• headache; or

• rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

What other drugs will affect Robinul?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect Robinul, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2025 Cerner Multum, Inc. Version: 5.01.